Table 1 Characteristics of the peritoneal dialysate effluent donors

From: Human peritoneal fibroblasts are a potent source of neutrophil-targeting cytokines: a key role of IL-1β stimulation

 

Patients with peritonitis

Stable patients with no peritonitis

 

Patient no. 1

Patient no. 2

Patient no. 3

Patient no. 4

Pooled PDE

Age (years)

73

62

39

78

Median (range) 61 (23–68)

Gender

F

F

F

M

M/F: 6/3

Underlying disease

Diabetes

Interstitial nephritis

Glomerulonephritis

Interstitial nephritis

Glomerulonephritis (4)

 

Hypertension

Nephrolithiasis

 

Nephrolithiasis

Diabetes (3)

 

Pyelonephritis

Hypertension

 

Hypertension

Unknown (2)

Etiology of peritonitis

Enterobacter cloacae

Enterococcus faecalis

Staphylococcus aureus, Streptococcus pyogenes

Bacteriological culture negative

 

Effluent (pg/ml)

     

 CXCL1

470

532

56

182

<15

 CXCL8

894

604

<15

386

Undetectable

 G-CSF

248

466

60

90

Undetectable

 sTNF-RI

3591

1639

1157

2778

ND

 sTNF-RII

5830

3762

1555

3058

ND

 IL-1β

34

39

Undetectable

<5

Undetectable

 TNFα

231

315

Undetectable

Undetectable

Undetectable

  1. ND, not determined.