Table 1 BUN and serum creatinine levels of adenine fed rats
From: High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy
BUN (mg/dl) | Weeks during adenine fed | Creatinine (mg/dl) | Weeks during adenine fed | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 4 | 8 | 12 | 16 | 20 | 0 | 4 | 8 | 12 | 16 | 20 | ||
Adenine (%) | Adenine (%) | ||||||||||||
0.25 | 18.7 (0.6) | 37.3** (2.5) | 62.0** (6.0) | 144.7** (5.8) | 206.7* (71.9) | 342.7** (40.3) | 0.25 | 0.60 (0.10) | 0.67 (0.06) | 1.77* (0.06) | 4.27** (0.21) | 5.23** (1.46) | 4.37** (0.59) |
0 | 17.6 (2.6) | 19.0 (1.7) | 22.0 (1.7) | 23.7 (9.1) | 22.0 (1.0) | 22.2 (2.1) | 0 | 0.57 (0.12) | 0.57 (0.06) | 1.27 (0.25) | 1.17 (0.12) | 1.13 (0.32) | 0.53 (0.06) |
BUN (mg/dl) | Weeks during adenine fed | Creatinine (mg/dl) | Weeks during adenine fed | ||||||||||
0 | 1 | 2 | 3 | 4 | 5 | 0 | 1 | 2 | 3 | 4 | 5 | ||
Adenine (%) | Adenine (%) | ||||||||||||
0.75 | 18.7 (0.6) | 32.5** (6.9) | 38.4** (2.6) | 44.0** (11.7) | 79.0** (26.9) | 150.0** (43.4) | 0.75 | 0.60 (0.10) | 0.88** (0.22) | 1.12** (0.13) | 1.40* (0.12) | 1.42* (0.63) | 1.73** (0.43) |
0.5 | 17.0 (2.6) | 29.3* (10.9) | 29.6** (5.8) | 37.4** (5.7) | 56.4** (4.8) | 68.3 (12.1) | 0.5 | 0.57 (0.12) | 0.70* (0.08) | 0.86 (0.13) | 0.98 (0.08) | 1.14 (0.22) | 1.60** (0.21) |
0.25 | 18.7 (0.6) | 14.8 (5.5) | 23.4 (8.3) | 14.8 (3.6) | 26.4 (7.5) | 33.5 (15.3) | 0.25 | 0.60 (0.10) | 0.50 (0.07) | 0.68 (0.15) | 0.86 (0.25) | 0.68 (0.16) | 0.95 (0.24) |
0 | 17.0 (2.6) | 12.0 (2.3) | 15.4 (2.9) | 7.8 (1.1) | 13.8 (3.2) | 12.0 (2.6) | 0 | 0.57 (0.12) | 0.40 (0.08) | 0.64 (0.11) | 0.90 (0.37) | 0.55 (0.17) | 0.60 (0.10) |
