Figure 4 | Modern Pathology

Figure 4

From: Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type

Figure 4

Ingenuity Pathway Analysis. Extracellular matrix genes of the ‘Connective Tissue Development and Function, Skeletal and Muscular System Development and Function, Tissue Development’ network (score 37) are downregulated in mucinous A vs histological grade- and molecular subtype-matched invasive ductal carcinomas (a), of the ‘Cell Morphology, Connective Tissue Development and Function, Tissue Development’ network (score 44) are downregulated in mucinous B vs histological grade- and molecular subtype-matched invasive ductal carcinomas (b), of the ‘Cancer, Reproductive System Disease, Ophthalmic Disease’ (score 43) are downregulated in neuroendocrine vs grade- and molecular subtype-matched invasive ductal carcinomas (c). Green: downregulation, red: upregulation. IDCs-NST: invasive ductal carcinomas of no special type.

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