Figure 8

Fibroblast focus. (a) Low magnification shows lightly staining fibroblast focus that is easily visible within background collagen in an area of honey-comb change. (b) Higher magnification showing spindle-shaped fibroblasts and myofibroblasts within lightly staining stroma. The cellular area contrasts sharply with adjacent collagen deposition (top), and the luminal surface is covered by alveolar epithelial lining cells.