Figure 9

Transbronchial biopsy specimen from UIP. This single tissue fragment obtained by TBB contains all the characteristic features necessary for diagnosing UIP. At low magnification (a) the typical variegated, patchwork pattern can be appreciated. There is a focus of honey-comb change (shown at high magnification in (b)), a fibroblast focus (arrow, and high magnification in (c)), and an area of relatively normal interstitium (arrowhead, and high magnification in (d)).