Table 2 Patient and tumor characteristics

From: Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma

Patient

Tumor

Age

Gender

Size

Laterality

Procedure

Fuhrman grade

Stage

Follow-up

PGL

GIST

Other renal tumors

Family history

1

1

72

M

4.0

R

Partial nephrectomy

2

pT1a

NA

No

No

Contralateral SDH-deficient RCC

None

1

2

  

9.0

L

Radical nephrectomy

2

pT2a

NA

No

No

Contralateral SDH-deficient RCC

None

2

3

54

M

2.9

R

Partial nephrectomy

3

pT1a

NED, 69 months

Yes

No

Contralateral oncocytoma (SDH retained), 1.0 cm ipsilateral mass cryoablated without biopsy

None

3

4

54

M

2.8

R

Partial nephrectomy

2

pT1a

NA

No

No

None

None

4

5

50

M

4.5

R

Radical nephrectomy

2

pT1b

NED, 8 months

No

No

None

Brother with renal cell carcinoma and liver metastasis

5

6

40

F

20.0

L

Radical nephrectomy

2

pT2b

DOD, 22 years

No

No

Small contralateral tumor, never resected

Personal history of BRCA2 mutation

6

7

40

F

8.5

R

Radical nephrectomy

2

pT2a

NED, 12 months

No

No

None

None

7

8

32

M

3.6

L

Radical nephrectomy

2

pT1a

NED, 1 month

No

No

None

None

8

9

25

M

2.4 cm (by CT scan)

L

Core biopsy

2

NA

NA

No

No

None

None

9

10

22

M

2.0

R

Partial nephrectomy

2

pT1a

NA

No

No

None

Brother with SDHB and FH mutations and related cancers

10

11

22

F

5.5

R

Radical nephrectomy

2

pT1b

NED, 18 months

Yes

No

None

None

  1. Abbreviations: DOD, died of disease; GIST, gastrointestinal stromal tumor; NA, not available; NED, no evidence of residual, recurrent, or metastatic disease; PGL, paraganglioma; RCC, renal cell carcinoma; SDH, succinate dehydrogenase.