Table 3 Results of immunohistochemical staining in SDH-deficient renal cell carcinoma
Patient | Tumor | SDHB | SDHA | PAX8 | Ksp-cad | S100A1 | EMA | AE1/AE3 | CAM 5.2 | CK7 | CD10 | RCC | AMACR | Chromogranin | Synaptophysin | Cathepsin K | TFE3 | HMB45 | CAIX | KIT | Vimentin | HNF1B |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | Lost | Retained | 100% | NA | 10% | 10% | 80% | NA | — | NA | NA | NA | NA | NA | NA | NA | NA | NA | Mast cells | Mast cells | Retained |
1 | 2 | Lost | Retained | NA | NA | NA | NA | NA | NA | — | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | Mast cells | NA |
2 | 3 | Lost | Retained | 100% | 100% | 5% | 80% | 80% | NA | 5% | — | NA | NA | NA | — | — | NA | NA | — | Mast cells | 40% | Retained |
3 | 4 | Lost | Retained | 100% | 90% | 80% | 60% | 30% | 90% | — | 30% | — | — | — | — | — | — | — | — | Mast cells | Mast cells | Retained |
4 | 5 | Lost | Retained | 100% | 100% | 5% | 5% | — | NA | — | — | NA | NA | — | NA | — | NA | NA | — | Mast cells | Mast cells | Retained |
5 | 6 | Lost | Retained | 90% | 90% | 80% | 60% | 10% | 10% | — | 60% | — | <5% | — | — | — | — | NA | — | Mast cells | NA | Retained |
6 | 7 | Lost | Retained | 100% | 100% | 90% | 50% | — | — | — | — | — | 80% | — | NA | — | — | NA | — | Mast cells | NA | Retained |
7 | 8 | Lost | Retained | 80% | 100% | 80% | 75% | — | — | — | — | — | 10% | — | — | — | — | NA | — | Mast cells | Mast cells | Retained |
8 | 9 | Lost | Lost | 100% | NA | 80% | 30% | — | — | — | — | — | <5% | — | NA | — | — | — | — | Mast cells | NA | Retained |
9 | 10 | Lost | Retained | 80% | 100% | 100% | 25% | — | 90% | — | — | — | 50% | — | — | — | — | — | — | Mast cells | Mast cells | Retained |
10 | 11 | Lost | Retained | 100% | 100% | 50% | 60% | — | — | — | 80% | — | — | — | NA | — | — | — | — | Mast cells | Mast cells | Retained |
