Extended Data Figure 3: Surface expression of the maturation markers CD62L and CD69 and lymph node egress are unchanged in Apom−/− mice. | Nature

Extended Data Figure 3: Surface expression of the maturation markers CD62L and CD69 and lymph node egress are unchanged in Apom−/− mice.

From: HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation

Extended Data Figure 3

ac, Surface expression of the lymphocyte maturation markers CD62L and CD69 was determined by flow cytometry and representative histograms are shown of staining by lymph node cells (a), thymocytes (b) or splenocytes (c) quantified in Extended Data Fig. 2 from wild-type (WT; red) and Apom−/− (blue) mice. d, Percentage of CD4+, CD8+ and CD19+ cells remaining in brachial and inguinal lymph nodes 14 h after administration of alpha-4 and alpha-L integrin-blocking antibodies. Circles represent mean value acquired from three mice in independent experiments; bars represent means.

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