Insects readily evolve resistance to insecticidal proteins that are introduced into genetically modified crop plants. Continuous directed evolution has now been used to engineer a toxin that overcomes insect resistance. See Article p.58
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Dovrat, D., Aharoni, A. Evolved to overcome Bt-toxin resistance. Nature 533, 39–40 (2016). https://doi.org/10.1038/nature17893
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DOI: https://doi.org/10.1038/nature17893
