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The 'anti-hype' vaccine

After years under the radar, RNA vaccines are finally emerging as immunotherapies to combat pandemics and cancer. But as Laura DeFrancesco reports, clinical validation remains elusive.

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Figure 1: Cytoplasmic delivery of a self-amplifying mRNA using a LNP non-viral delivery system.

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DeFrancesco, L. The 'anti-hype' vaccine. Nat Biotechnol 35, 193–197 (2017). https://doi.org/10.1038/nbt.3812

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