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Protein delivery using VP22

Nature Biotechnology volume 20, page 20 (2002)Cite this article

A Correction to this article was published on 01 April 2002

To the editor

The herpes simplex virus protein VP22 has been reported to translocate between cultured mammalian cells1. VP22 expressed in cultured cells is exported and spreads to surrounding cells, where it accumulates in the nuclei. The activity of the VP22 protein can also deliver heterologous protein sequences, making it a unique and useful tool to study molecular and cellular processes.

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Figure 1: Translocation of VP22–Flp protein fusion.
Figure 2: Delivery of T7 RNA Polymerase (RNAP).

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  1. Research and Development, Invitrogen Corporation, 1600 Faraday Avenue, Carlsbad, 92008, CA

    Robert P. Bennett & Brian Dalby

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  1. Robert P. Bennett
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  2. Brian Dalby
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Bennett, R., Dalby, B. Protein delivery using VP22. Nat Biotechnol 20, 20 (2002). https://doi.org/10.1038/nbt0102-20

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