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The dynamic organizer

Nature Cell Biology volume 1, pages E179–E181 (1999)Cite this article

Abstract

The organizer is a region in gastrulating embryos that induces and patterns the body axis. New research shows that induction of organizer formation is regulated by interplay of inducing and inhibiting ligands that affect the cells as they migrate through the organizer.

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Figure 1: The node cell population changes continuously1.
Figure 2: A feedback mechanism regulating node induction during gastrulation.

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Authors and Affiliations

  1. Department of Genetics, Harvard Medical School, Boston, 02115, Massachusetts, USA

    Ronen Schweitzer & Clifford J. Tabin

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  1. Ronen Schweitzer
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  2. Clifford J. Tabin
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Correspondence to Clifford J. Tabin.

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Schweitzer, R., Tabin, C. The dynamic organizer. Nat Cell Biol 1, E179–E181 (1999). https://doi.org/10.1038/15616

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