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Pulmonary fibrosis in systemic sclerosis: is treatment with cyclophosphamide more effective than placebo?

Nature Clinical Practice Rheumatology volume 3, pages 372–373 (2007)Cite this article

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boxed-textHoyles RK et al. (2006) A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma. Arthritis Rheum 54: 3962–3970

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References

  1. White B et al. (2000) Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitis. Ann Intern Med 132: 947–954

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  2. Giacomelli R et al. (2002) Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis. J Rheumatol 29: 731–736

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Acknowledgements

The synopsis was written by I Miniati, M Matucci Cerinic and Jasmine Farsarakis, Associate Editor, Nature Clinical Practice.

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  1. I Miniati is a Rheumatologist PhD Candidate and M Matucci Cerinic is Professor of Rheumatology and Medicine in the Department of Medicine, Division of Rheumatology, DENOThe Center at the University of Florence, Florence, Italy.,

    Irene Miniati & Marco Matucci Cerinic

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  1. Irene Miniati
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  2. Marco Matucci Cerinic
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Correspondence to Marco Matucci Cerinic.

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The authors declare no competing financial interests.

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Miniati, I., Matucci Cerinic, M. Pulmonary fibrosis in systemic sclerosis: is treatment with cyclophosphamide more effective than placebo?. Nat Rev Rheumatol 3, 372–373 (2007). https://doi.org/10.1038/ncprheum0507

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