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Prostate cancer: adenovirus-mediated imaging of sentinel node metastasis

Nature Clinical Practice Urology volume 5, page 580 (2008)Cite this article

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Burton JB et al. (2008) Adenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer. Nat Med 14: 882–888

Lymph node status in prostate cancer is an important predictor of outcome, but currently, no reliable, noninvasive methods exist to detect lymph node metastasis. Now, researchers at the University of California, Los Angeles, describe the use of an adenovirus vector to allow direct imaging of metastasis in sentinel lymph nodes. Their study used a mouse xenograft model of human prostate cancer.

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Prostate cancer: adenovirus-mediated imaging of sentinel node metastasis. Nat Rev Urol 5, 580 (2008). https://doi.org/10.1038/ncpuro1207

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