Supplementary Figure 1: POP3 is a previously undescribed gene located between IFI16 and IFIX.

(a) cDNA showing the open reading frame of POP3 (Genbank accession number: KF562078) (b) A nucleotide BLAST (blastn) analysis against the assembled human RefSeq genomes (http://blast.ncbi.nlm.nih.gov) detailing the genomic location of POP3 within the HIN-200 cluster flanked by IFI16 and PYHIN1 on human chromosome 1q23.