Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Correspondence
  • Published:

Reply to “Nasal colonization by Staphylococcus aureus”

Nature Medicine volume 10, page 447 (2004)Cite this article

Access through your institution
Buy or subscribe

Peschel et al. reply:

Colonization of the anterior nares of healthy individuals by S. aureus leads to an increased risk of nosocomial infections. We have recently shown that WTA polymers on the staphylococcal cell surface are essential for nasal colonization in a cotton rat model and mediate specific interaction with human nasal epithelial cells1. A WTA-deficient mutant was rapidly and completely lost from the nares, and preinstillation with purified WTA interfered with nasal colonization.

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Weidenmaier, C. et al. Nat. Med. 10, 243–245 (2004).

    Article  CAS  Google Scholar 

  2. O'Brien, L.M., Walsh, E.J., Massey, R.C., Peacock, S.J. & Foster, T.J. Cell. Microbiol. 4, 759–770 (2002).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medical Microbiology and Hygiene Department, Cellular and Molecular Microbiology, University of Tübingen, Tübingen, 70276, Germany

    Christopher Weidenmaier & Andreas Peschel

  2. Biosynexus Inc., Gaithersburg, 20877, Maryland, USA

    John F. Kokai-Kun

Authors
  1. Christopher Weidenmaier
    View author publications

    Search author on:PubMed Google Scholar

  2. John F. Kokai-Kun
    View author publications

    Search author on:PubMed Google Scholar

  3. Andreas Peschel
    View author publications

    Search author on:PubMed Google Scholar

Ethics declarations

Competing interests

Biosynexus has filed a patent application pertaining to this work.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Weidenmaier, C., Kokai-Kun, J. & Peschel, A. Reply to “Nasal colonization by Staphylococcus aureus” . Nat Med 10, 447 (2004). https://doi.org/10.1038/nm0504-447b

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/nm0504-447b

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing