Genome engineering skews the sex ratio of malaria-carrying mosquitoes heavily toward males and leads to a population crash.
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References
Galizi, R. et al. A synthetic sex ratio distortion system for the control of the human malaria mosquito. Nat. Commun. 5, 3977 (2014).
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Rusk, N. Targeted nucleases fight malaria. Nat Methods 11, 793 (2014). https://doi.org/10.1038/nmeth.3060
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DOI: https://doi.org/10.1038/nmeth.3060