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This study uses a transgenic mouse line expressing Cre-inducible astro-hM3Dq to study astrocytes’ role in neuroinflammation and cognition without the use of viral transduction, mitigating the potential side effects associated with standard techniques.
A molecular analysis of axolotl limb regeneration has identified a positive genetic circuit that maintains posterior cell identity and can be used to reprogramme anterior cells into posterior cells.