Researchers report an optical method to detect and image single proteins without using any labels.
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References
Piliarik, M. & Sandoghdar, V. Direct optical sensing of single unlabelled proteins and super-resolution imaging of their binding sites. Nat. Commun. 5, 4495 (2014).
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Doerr, A. Imaging without labels. Nat Methods 11, 990 (2014). https://doi.org/10.1038/nmeth.3129
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DOI: https://doi.org/10.1038/nmeth.3129