Supplementary Figure 3: Cross-sectional views of representative animals. | Nature Methods

Supplementary Figure 3: Cross-sectional views of representative animals.

From: Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques

Supplementary Figure 3

a. Cross-sections of the frontal torso and abdomen of SIV infected viremic monkey Viremic 2. Each slice is 1.37 mm thick; 28 slices are displayed, amounting to a frontal view every 2.74 mm. A SIV positive signal is apparent throughout the gastrointestinal tract, especially within the ileum, jejunum and colon, and within the lung. Background signal, as expected, was high within the liver, heart, and kidneys. b. Cross-sections of the frontal torso and abdomen of SIV infected viremic monkey Viremic 1. Each slice is 1.37 mm thick; 24 slices are displayed, amounting to a frontal view every 2.74 mm. A SIV positive signal is apparent throughout the GI tract and within the lung. Background signal, as expected, was high within the liver, heart, and kidneys. c. Cross-sections of the frontal torso and abdomen of uninfected monkey Control 1 given modified 7D3. In the frontal views, each slice is 0.98 mm thick, 24 slices are displayed, amounting to a frontal view every 1.96 mm. Very little signal above muscle background within the gastrointestinal tract, and lymph nodes. Background signal, as expected, was high within the liver, heart, and kidneys, and measurable within the lung.

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