Table 2 The frequency of CYP2D6 gene copy number variations
From: Genetic matters of CYP2D6 in breast cancer: copy number variations and nucleotide polymorphisms
Alleles | Frequency according to ethnicity (%) | |||
|---|---|---|---|---|
Caucasians | Asians | African Americans | Ethiopians and Saudi Arabians | |
Null* | 2–8 | 4–6 | 6–7 | 0–3 |
One | ∼85 | ∼95 | ∼90 | ∼80 |
Duplicated‡ and multiplicated (≥3) | 1–7 | 0–1 | 2 | 10–14 |
*Null denotes an allele of CYP2D6 gene deletion (also known as CYP2D6*5).‡The frequency is estimated for duplication and multiplication together. Data from REFS 7,12. | ||||
