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Pancreatic cancer

PDAC subtypes

Nature Reviews Cancer volume 15, page 575 (2015)Cite this article

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By separating genomics data from the predicted cellular source (such as stromal cell versus pancreatic tumour cell), Moffitt et al. have identified subtypes of pancreatic adenocarcinoma (PDAC). They characterized a basal-like subtype that has a worse prognosis than the subtype with activated stroma.

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References

  1. Moffitt, R. A. et al. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma. Nat. Genet. http://dx.doi.org/10.1038/ng.3398 (2015)

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  1. Gemma K. Alderton
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Alderton, G. PDAC subtypes. Nat Rev Cancer 15, 575 (2015). https://doi.org/10.1038/nrc4025

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