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Thyroid function

The monoaminergic system might mediate the link between dysregulation of the TSH receptor and ADHD

Nature Reviews Endocrinology volume 10, page 512 (2014)Cite this article

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Mice with a knockout of the TSH receptor display behavioural and cognitive features characteristic of attention deficit/hyperactivity disorder (ADHD). Some of these features were reversed by treatment with methylphenidate, a drug used in ADHD therapy that blocks the dopamine and norepinephrine transporters. Analysis of the knockout mice revealed monoaminergic changes in several brain regions.

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References

  1. Mouri, A. et al. Thyrotoropin receptor knockout changes monoaminergic neuronal system and produces methylphenidate-sensitive emotional and cognitive dysfunction. Psychoneuroendocrinology 10.1016/j.psyneuen.2014.05.021

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The monoaminergic system might mediate the link between dysregulation of the TSH receptor and ADHD. Nat Rev Endocrinol 10, 512 (2014). https://doi.org/10.1038/nrendo.2014.113

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