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Endoscopy

Nitrous oxide sedation for colonoscopy—no laughing matter

Moderate sedation is typically used during lower gastrointestinal endoscopy procedures. Deep sedation with propofol is becoming widespread but carries the risk of cardiorespiratory depression. Nitrous oxide is an inhaled sedative administered routinely in dentistry that might prove to be a safe option for sedation during lower gastrointestinal endoscopy.

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Correspondence to Todd H. Baron.

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Rao, A., Baron, T. Nitrous oxide sedation for colonoscopy—no laughing matter. Nat Rev Gastroenterol Hepatol 7, 539–541 (2010). https://doi.org/10.1038/nrgastro.2010.148

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