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Probiotic helps to eradicate H. pylori

Nature Reviews Gastroenterology & Hepatology volume 7, page 362 (2010)Cite this article

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The probiotic Saccharomyces boulardii could improve the efficacy of triple therapy for Helicobacter pylori eradication, according to a Korean research group. “This addition [of S. boulardii] clearly led to higher ... eradication rates and lessened side effects,” write the researchers.

Guidelines currently recommend that H. pylori eradication therapy should comprise ≥7 days of treatment with a PPI and two antibiotics. However, eradication rates with this triple therapy are falling, as a result of increased antibiotic resistance and poor adherence to treatment (related to adverse events, such as diarrhea and epigastric pain).

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ORIGINAL RESEARCH PAPER

  1. Song. M. J. et al. The effect of probiotics and mucoprotective agents on PPI-based triple therapy for eradication of Helicobacter pylori. Helicobacter 15, 206–213 (2010)

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  1. Claire Greenhill
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Greenhill, C. Probiotic helps to eradicate H. pylori. Nat Rev Gastroenterol Hepatol 7, 362 (2010). https://doi.org/10.1038/nrgastro.2010.86

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  • DOI: https://doi.org/10.1038/nrgastro.2010.86

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