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Intestinal tract

DLL4 signalling maintains organization and function of lacteals

Nature Reviews Gastroenterology & Hepatology volume 13, page 3 (2016)Cite this article

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New molecular insights into maintenance and regeneration of lacteals, specialized lymphatic vessels in the villi of the small intestine, have been reported in a recent study published in The Journal of Clinical Investigation.

Although often overlooked in research, the intestinal lymphatic vasculature adopts key functions in the small intestine, regulates absorption and transport of fatty acids, and encourages an active crosstalk between immune cells in the area.

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References

  1. Bernier-Latmani, J. et al. DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. J. Clin. Invest. 10.1172/JCI82045

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  1. Christine Weber
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Weber, C. DLL4 signalling maintains organization and function of lacteals. Nat Rev Gastroenterol Hepatol 13, 3 (2016). https://doi.org/10.1038/nrgastro.2015.201

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  • DOI: https://doi.org/10.1038/nrgastro.2015.201

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