Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

Molecular motors

Run rings around

Nature Reviews Molecular Cell Biology volume 7, page 792 (2006)Cite this article

Access through your institution
Buy or subscribe

Most kinesins use energy from ATP hydrolysis to move and generate force along microtubules; however, exceptions exist. Rather than moving along microtubules, kinesin-13 proteins (kinesin-13s) actively depolymerize microtubules, which is important for chromosome segregation during mitosis. What is the structural basis of this unusual behaviour by kinesin-13s? And what is the mechanism that is used to depolymerize microtubules? Tan et al. now provide some answers.

They found that kinesin-13s form rings and spirals around microtubules...

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

ORIGINAL RESEARCH PAPER

  1. Tan, D. et al. Kinesin-13s form rings around microtubules. J. Cell Biol. 2 Oct 2006 (doi: 10.1083/jcb.200605194)

Download references

Authors
  1. Ekat Kritikou
    View author publications

    Search author on:PubMed Google Scholar

Related links

Related links

WEB SITE

Hernando Sosa's laboratory

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kritikou, E. Run rings around. Nat Rev Mol Cell Biol 7, 792 (2006). https://doi.org/10.1038/nrm2049

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/nrm2049

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing