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Epigenetics

A silent inheritance

Nature Reviews Molecular Cell Biology volume 10, page 304 (2009)Cite this article

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Chromatin templates that are bound by the PRC1 core complex (PCC) prior to DNA replication are completely replicated in vitro. Notably, the known inhibitory effect of PCC on chromatin remodelling persists through chromatin replication. So, PCC binds to, and affects, chromatin through DNA replication in vitro.

Polycomb repressor complex 1 (PRC1) proteins remain bound to chromatin during DNA replication...

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References

ORIGINAL RESEARCH PAPER

  1. Francis, N. J. et al. Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell 137, 110–122 (2009)

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FURTHER READING

  1. Probst, A. V. et al. Epigenetic inheritance during the cell cycle. Nature Rev. Mol. Cell Biol. 10, 192–206 (2009)

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Authors
  1. Francesca Cesari
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Cesari, F. A silent inheritance . Nat Rev Mol Cell Biol 10, 304 (2009). https://doi.org/10.1038/nrm2682

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