Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

Bacterial pathogenesis

First aid kit for cholera

Nature Reviews Microbiology volume 12, page 726 (2014)Cite this article

Subjects

Access through your institution
Buy or subscribe

The authors used a metagenomics approach to analyse the bacterial composition of faecal samples collected from seven infected Bangladeshi adults and healthy controls. They showed that during the early phases of diarrhoea, the microbiota was divergent from the healthy adult microbiota, with V. cholerae as well as Streptococcus and Fusobacterium species being dominant, while during recovery, a healthy microbial community, including Bacteriodes, Ruminococcus and Prevotella species, was restored. Interestingly, several bacterial species that have previously been shown to be associated with the assembly and maturation of the gut microbiota in healthy Bangladeshi children were present in samples collected during the recovery phase. This suggests that similar processes underlie normal postnatal community assembly and microbiota restoration after disruption.

R. obeum restricted pathogen colonization and reduced the expression of V. cholerae virulence factors

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hsiao, A. et al. Members of the human gut microbiota involved in recovery from Vibrio cholerae infection. Nature http://dx.doi.org/10.1038/nature13738 (2014)

Download references

Authors
  1. Andrea Du Toit
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Du Toit, A. First aid kit for cholera. Nat Rev Microbiol 12, 726 (2014). https://doi.org/10.1038/nrmicro3366

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/nrmicro3366

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing