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Volume 24 Issue 3, March 2026

Magnetotactic bacteria, inspired by the Review on p168

Cover design: Richard Tibbitts

Research Highlights

  • This study reports that the tree bark microbial community actively modulates fluxes of climate-active gases and volatile organic compounds, and may mediate global atmospheric gas cycling.

    • Andrea Du Toit
    Research Highlight

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  • A recent study identifies a compound that sensitizes fungal pathogens to the antifungal drug caspofungin.

    • Michael Attwaters
    Research Highlight
  • This study shows that microgravity modulates phage–host co-evolution and alters their mutational landscapes, facilitating adaptation to such a distinct environmental niche.

    • Andrea Du Toit
    Research Highlight
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Journal Club

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News & Analysis

  • This Genome Watch discusses the great biosynthetic capacity that has been identified in marine environmental and host-associated microbiomes, along with approaches to facilitate research into these diverse and resource-rich microbial communities.

    • Peter Osborne
    • Keir J. Macartney
    • Matthew G. Miyada
    Genome Watch
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Reviews

  • In this Review, Weingarth and colleagues discuss both recently discovered compounds and established envelope-targeting antibiotics, including compounds that target Gram-positive bacteria, more complex Gram-negative bacteria and mycobacterial pathogens, with a particular focus on their drug–target interactions.

    • Charalampos Ntallis
    • Nathaniel I. Martin
    • Markus Weingarth
    Review Article
  • Fusobacterium nucleatum is a commensal microorganism and opportunistic pathogen, with a pathogenic role in periodontal disease, inflammatory bowel disease and various cancers, most notably colorectal cancer. This Review discusses F. nucleatum and its ecological niches and virulence factors, links with disease, oncogenic mechanisms, and emerging diagnostic approaches and therapeutic strategies.

    • Shan-Shan Jiang
    • Ying-Xuan Chen
    • Jing-Yuan Fang
    Review Article
  • Clostridioides difficile infection is challenging to diagnose and treat and is associated with considerable mortality, morbidity and economic costs worldwide. In this Review, Chilton et al. discuss changes in global epidemiology, breakthroughs in pathogenesis and antibiotic resistance, the role of microbiota dysbiosis and the potential for microbiota-based therapeutics for Clostridioides difficile infection.

    • Caroline H. Chilton
    • Virginie Viprey
    • Mark H. Wilcox
    Review Article
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