Several randomized clinical trials with short-term follow-up have shown that patients on hemodialysis with prophylactic antibiotic catheter locks have reduced catheter-related bacteremia. However, the long-term safety of such locks remains a subject of ongoing debate. Landry et al. now report that prophylactic gentamicin catheter locks can promote the emergence of gentamicin-resistant bacteremia during long-term use.
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M. Allon has worked as a consultant for CorMedix.
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Allon, M. Are prophylactic gentamicin catheter locks safe?. Nat Rev Nephrol 7, 8–10 (2011). https://doi.org/10.1038/nrneph.2010.140
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DOI: https://doi.org/10.1038/nrneph.2010.140
