Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

Transplantation

Good long-term outcomes after pediatric en bloc transplantation

Nature Reviews Nephrology volume 7, page 546 (2011)Cite this article

Subjects

The lack of donor organs available for patients with end-stage renal disease has led to the use of expanded criteria kidney donors. A retrospective analysis comparing long-term outcomes following en bloc pediatric kidney transplantation (EBKT), living donor kidney transplantation (LDKT) and standard criteria deceased donor kidney transplantation (SDKT) in adult recipients shows that EBKT is a viable strategy to help address the organ deficit.

Technical difficulties and complications have led to a reluctance to perform EBKT, especially when the donor weighs <10 kg. However, evidence has shown that EBKT has better outcomes than adult SDKT. “At the Hume-Lee Transplant Center, we have been performing these technically challenging transplantations for the past 25–30 years to meet the shortage of adult kidneys from deceased donors,” says Amit Sharma, an author on the recent paper. “Numerous reports have compared the outcomes of EBKT with SDKT. Ours is only the second report comparing the outcomes of these pediatric kidneys with LDKT.”

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

ORIGINAL RESEARCH PAPER

  1. Sharma, A. et al. En bloc kidney transplantation from pediatric donors: comparable outcomes with living donor kidney transplantation. Transplantation http://dx.doi.org/10.1097/TP.0b013e3182279107

Download references

Authors
  1. Helene Myrvang
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Myrvang, H. Good long-term outcomes after pediatric en bloc transplantation. Nat Rev Nephrol 7, 546 (2011). https://doi.org/10.1038/nrneph.2011.119

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/nrneph.2011.119

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing