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Chronic kidney disease

Estimating GFR—the right equation for the right population

A comparison by Selistre et al. of several creatinine-based equations commonly used to estimate glomerular filtration rate (GFR) shows that equations developed in adult populations result in substantial overestimation of GFR in adolescents and young adults. Equations developed in pediatric populations were found to have superior performance, but limitations remain for all estimates.

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Astor, B. Estimating GFR—the right equation for the right population. Nat Rev Nephrol 8, 379–380 (2012). https://doi.org/10.1038/nrneph.2012.114

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