Renal transplant recipients who receive larger donor kidneys relative to their own body weight may have better kidney function at 12 months than those who receive smaller kidneys, according to a recent paper. Sikora and co-workers calculated the 'volume dose'—the ratio of donor kidney volume to recipient weight—of 125 living kidney donor-to-recipient pairs. Transplant recipients in the highest tertile of volume dose had a reduced risk of developing an eGFR of <60 ml/min/1.73 m2 (odds ratio 0.23, 95% CI 0.07–0.81).
ORIGINAL RESEARCH PAPER
Sikora, S. et al. Effect of donor kidney volume on recipient outcome: does the “dose” matter? Transplantation doi:10.1097/TP.0b013e31826f135e
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Larger donor kidneys may improve recipient outcome. Nat Rev Nephrol 8, 683 (2012). https://doi.org/10.1038/nrneph.2012.232
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DOI: https://doi.org/10.1038/nrneph.2012.232