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Acute kidney injury

Atorvastatin may reduce risk of contrast-induced AKI

Nature Reviews Nephrology volume 9, page 66 (2013)Cite this article

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The addition of high-dose atorvastatin potentiates this prophylactic effect

The addition of atorvastatin to hydration therapy and N-acetylcysteine (NAC) reduces the incidence of acute kidney injury (AKI) in patients receiving iodinated contrast media, according to new research. “The present study confirms the effectiveness of the combined approach with hydration and high-dose NAC in preventing contrast-induced AKI. The addition of high-dose atorvastatin potentiates this prophylactic effect,” explains researcher Carlo Briguori.

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ORIGINAL RESEARCH PAPER

  1. Quintavalle, C. et al. Impact of a high loading dose of atorvastatin on contrast-induced acute kidney injury. Circulation doi:10.1161/CIRCULATIONAHA.112.103317

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Authors
  1. Susan J. Allison
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Allison, S. Atorvastatin may reduce risk of contrast-induced AKI. Nat Rev Nephrol 9, 66 (2013). https://doi.org/10.1038/nrneph.2012.277

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