Patients with end-stage renal disease typically receive three 3–4 h haemodialysis sessions per week. Although available data from well-powered randomized trials are limited, studies published in 2012 provided new evidence that haemodialysis regimens with longer treatment times and/or a higher frequency of sessions might reduce the high morbidity and mortality of patients on maintenance dialysis.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology
Journal of Nephrology Open Access 22 May 2019
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
References
Lowrie, E. G., Laird, N. M., Parker, T. F. & Sargent, J. A. Effect of the hemodialysis prescription of patient morbidity: report from the National Cooperative Dialysis Study. N. Engl. J. Med. 305, 1176–1181 (1981).
Innes, A., Charra, B., Burden, R. P., Morgan, A. G. & Laurent, G. The effect of long, slow haemodialysis on patient survival. Nephrol. Dial. Transplant. 14, 919–922 (1999).
Pauly, R. P. et al. Survival among nocturnal home haemodialysis patients compared to kidney transplant recipients. Nephrol. Dial. Transplant. 24, 2915–2919 (2009).
Lacson, E. et al. Survival with three-times weekly in-center nocturnal versus conventional hemodialysis. J. Am. Soc. Nephrol. 23, 687–695 (2012).
Foley, R. N., Gilbertson, D. T., Murray, T. & Collins, A. J. Long interdialytic interval and mortality among patients receiving hemodialysis. N. Engl. J. Med. 365, 1099–1107 (2011).
Chertow, G. M. et al. In-center hemodialysis six times per week versus three times per week. N. Engl. J. Med. 363, 2287–2300 (2010).
Weinhandl, E. D., Liu, J., Gilbertson, D. T., Arneson, T. J. & Collins, A. J. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. J. Am. Soc. Nephrol. 23, 895–904 (2012).
Culleton, B. F. et al. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial. JAMA 298, 1291–1299 (2007).
Rocco, M. V. et al. The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int. 80, 1080–1091 (2011).
Nesrallah, G. E. et al. Intensive hemodialysis associates with improved survival compared with conventional hemodialysis. J. Am. Soc. Nephrol. 23, 696–705 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
R. Mehrotra has received grant or research support from DaVita. J. Himmelfarb declares no competing interests.
Rights and permissions
About this article
Cite this article
Mehrotra, R., Himmelfarb, J. Could longer and more frequent haemodialysis improve outcomes?. Nat Rev Nephrol 9, 74–75 (2013). https://doi.org/10.1038/nrneph.2012.287
Published:
Issue date:
DOI: https://doi.org/10.1038/nrneph.2012.287
This article is cited by
-
Management of hyperkalemia in patients with kidney disease: a position paper endorsed by the Italian Society of Nephrology
Journal of Nephrology (2019)
-
Dialysis frequency versus dialysis time, that is the question
Kidney International (2014)