Several studies published in 2014 might facilitate improvements in the treatment and long-term care of renal transplant recipients. The potential risks of living kidney donation, the efficacy and safety of alemtuzumab-based induction therapy, and the treatment of chronic hepatitis E virus infection have been addressed.
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References
Muzaale, A. D. et al. Risk of end-stage renal disease following live kidney donation. JAMA 311, 579–586 (2014).
Ibrahim H. N. et al. Long-term consequences of kidney donation. N. Engl. J. Med. 360, 459–469 (2009).
Cherikh, W. S., Young, C. J., Kramer, B. F., Taranto, S. E., Randall, H. B. & Fan, P.-Y. Ethnic and gender related differences in the risk of end-stage renal disease after living kidney donation. Am. J. Transplant. 11, 1650–1655 (2011).
Mjøen, G. et al. Long-term risks for kidney donors. Kidney Int. 86, 162–167 (2014).
Morgan, R. D., O'Callaghan, J. M., Knight, S. R. & Morris, P. J. Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis. Transplantation 93, 1179–1188 (2012).
Hanaway, M. J. et al. Alemtuzumab induction in renal transplantation. N. Engl. J. Med. 364, 1909–1919 (2011).
The 3C Study Collaborative Group. Alemtuzumab-based induction treatment versus basiliximab-based induction treatment in kidney transplantation (the 3C study): a randomised trial. Lancet 384, 1684–1690 (2014).
Haynes, R. et al. on behalf of The 3C Study Collaborative Group. Campath, calcineurin inhibitor reduction and chronic allograft nephropathy (3C) study: background, rationale, and study protocol. Transplant. Res. 2, 7 (2013).
Kamar, N. et al. Ribavirin for chronic hepatitis E virus infection in transplant recipients. N. Engl. J. Med. 370, 1111–1120 (2014).
Kamar, N. et al. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants. Gastroenterology 140, 1481–1489 (2011).
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Hesselink, D., Weimar, W. Renal transplantation—reducing risk and improving outcome. Nat Rev Nephrol 11, 72–73 (2015). https://doi.org/10.1038/nrneph.2014.240
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DOI: https://doi.org/10.1038/nrneph.2014.240
