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Chronic kidney disease

ECGs help predict risk of death in CKD

Nature Reviews Nephrology volume 11, page 505 (2015)Cite this article

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The standard 12-lead electrocardiogram (ECG) is a routine diagnostic test that provides a comprehensive overview of cardiac arrhythmias and conduction, but debate exists regarding its utility in low and intermediate-risk populations, such as those with chronic kidney disease (CKD). Now, findings from the Chronic Renal Insufficiency Cohort demonstrate that ECG measures are independent markers for risk of cardiovascular death in patients with CKD.

The investigators found that a prolonged PR and QT interval, wide QRS duration, and increased heart rate were independent risk factors for cardiovascular death, more so than for non-cardiovascular death or all-cause mortality. When these measures were added to a comprehensive model of cardiorenal risk factors, the prediction of cardiovascular death markedly improved.

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References

  1. Deo, R. et al. Electrocardiographic measures and prediction of cardiovascular and noncardiovascular death in CKD. J. Am. Soc. Nephrol. 10.1681/ASN.2014101045

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  1. Jessica K. Edwards
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Edwards, J. ECGs help predict risk of death in CKD. Nat Rev Nephrol 11, 505 (2015). https://doi.org/10.1038/nrneph.2015.129

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  • DOI: https://doi.org/10.1038/nrneph.2015.129

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