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Prostate cancer

Anterior perirectal fat: a barrier to optimal outcomes in patients undergoing HIFU therapy

Nature Reviews Urology volume 7, page 591 (2010)Cite this article

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The patients were classified as being obese (n = 48), overweight (n = 24) or of normal weight (n = 43) according to the Western Pacific Regional Office WHO criteria, which takes into account the difference in body shape and build between Westerners and South-East Asians.

The 5-year disease-free survival rates in the obese, overweight and normal-weight groups were 55.5%, 90.8% and 83.9%, respectively (log-rank P <0.01). BMI was significantly correlated with APFT thickness (the mean of thickness measured at three different sites), and multivariate analysis indicated that APFT thickness was a significant predictor of disease-free survival.

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ORIGINAL RESEARCH PAPER

  1. Sumitomo, M. et al. Anterior perirectal fat tissue thickness is a strong predictor of recurrence after high-intensity focused ultrasound for prostate cancer. Int. J. Urol. 17, 776–783 (2010)

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  1. Nick Warde
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Warde, N. Anterior perirectal fat: a barrier to optimal outcomes in patients undergoing HIFU therapy. Nat Rev Urol 7, 591 (2010). https://doi.org/10.1038/nrurol.2010.170

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