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Kidney cancer

Better surgery selection criteria

Nature Reviews Urology volume 7, page 592 (2010)Cite this article

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Cytoreductive nephrectomy is a standard of care for metastatic renal cell carcinoma (RCC). There is, however, a subset of patients who derive no benefit from this procedure. Until now, tools with which to identify these patients have been lacking.

Christopher Wood and colleagues from the University of Texas retrospectively investigated the overall survival of almost 700 patients with metastatic RCC who had received medical therapy; that is, immunotherapy, systemic targeted therapy, and/or chemotherapy. In addition to medical therapy, 566 patients underwent cytoreductive nephrectomy. The surgery cohort was subdivided into two groups, based on when their overall survival diverged from that of the nonsurgery patients.

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ORIGINAL RESEARCH PAPER

  1. Culp, S. H. et al. Can we better select patients with metastatic renal cell carcinoma for cytoreductive nephrectomy? Cancer 116, 3378–3388 (2010)

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  1. Rebecca Drake
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Drake, R. Better surgery selection criteria. Nat Rev Urol 7, 592 (2010). https://doi.org/10.1038/nrurol.2010.173

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  • DOI: https://doi.org/10.1038/nrurol.2010.173

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