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Prostate cancer

Post-diagnosis diet and the risk of progression

Nature Reviews Urology volume 7, page 57 (2010)Cite this article

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The marked discrepancy in survival between men with localized prostate cancer and those with advanced disease makes the search for modifiable factors that influence progression of prime importance. Two new studies implicate ingestion of eggs, poultry with skin, and certain fatty acids in advancement of prostatic malignancy.

Speculation about interactions between diet and cancer began several decades ago. Interest in this area was initially piqued by epidemiological observations of marked variation in disease incidence between populations with contrasting eating habits. Several associations have been detected between prostate cancer occurrence and nutritive factors, such as saturated fat, soy proteins, and lycopenes. The bulk of research effort has, however, been directed towards risk of disease development, rather than likelihood of progression.

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ORIGINAL RESEARCH PAPERS

  1. Richman, E. L. et al. Intakes of meat, fish, poultry, and eggs and risk of prostate cancer progression. Am. J. Clin. Nutr. doi:10.3945/ajcn.2009.28474

  2. Aronson, W. J. et al. Growth inhibitory effect of low fat diet on prostate cancer cells: results of a prospective, randomized dietary intervention trial in men with prostate cancer. J. Urol. 183, 345–350 (2010)

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  1. Suzanne J. Farley
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Farley, S. Post-diagnosis diet and the risk of progression. Nat Rev Urol 7, 57 (2010). https://doi.org/10.1038/nrurol.2010.5

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