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Untangling LUTS, BPH and renal function

Nature Reviews Urology volume 8, page 648 (2011)Cite this article

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...the etiology and underlying mechanisms of LUTS are unclear...

Lower urinary tract symptoms (LUTS), which include storage, voiding and postmicturition symptoms, occur in a considerable proportion of men over the age of 40 years. These findings are often attributed to bladder outlet obstruction secondary to benign prostatic hyperplasia (BPH); however, other conditions are also thought to cause LUTS, such as detrusor overactivity (which is predominantly associated with storage symptoms). In short, the etiology and underlying mechanisms of LUTS are unclear, and the optimal evaluation and management of patients with these symptoms remain elusive. Two large studies provide interesting food for thought regarding these issues.

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ORIGINAL RESEARCH PAPERS

  1. Kaplan, S. A. et al. Add-on fesoterodine for residual storage symptoms suggestive of overactive bladder in men receiving α-blocker treatment for lower urinary tract symptoms. BJU Int. doi:10.1111/j.1464-410X.2011.10624.x

    Article  PubMed  Google Scholar 

  2. Kwon, Y.-M. et al. Lower urinary tract symptoms have negative associations with glomerular filtration rate irrespective of prostate volume in Korean men. J. Urol. doi:10.1016/j.urology.2011.08.011

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  1. Nick Warde
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Warde, N. Untangling LUTS, BPH and renal function. Nat Rev Urol 8, 648 (2011). https://doi.org/10.1038/nrurol.2011.183

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