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Promising future for the prostatic urethral lift

Nature Reviews Urology volume 10, page 677 (2013)Cite this article

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Benefits of the prostatic urethral lift for men with lower urinary tract symptoms (LUTS) have been confirmed in a crossover study of the device, recently published in BJU International. “This study is a post hoc analysis of data from the LIFT (Luminal Improvement Following Prostatic Tissue Approximation for the Treatment of LUTS secondary to BPH) study that was published a few months ago,” explains corresponding author Henry Woo. Both studies demonstrated quick and durable improvements in symptoms and flow, as well as preservation of sexual function.

Crossover studies are commonly used to compare the relative effects of pharmaceutical therapies, but surgical interventions and medical devices are harder to assess in this context because patients who have already undergone the intervention cannot then undergo a sham procedure. Instead, Woo and colleagues performed a one-way crossover study, whereby men who initially received the sham were later offered the lift procedure, and each patient acted as their own control.

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References

  1. Cantwell, A. L. et al. Multi-center prospective crossover study of the prostatic urethral lift for the treatment of LUTS secondary to BPH. BJU Int. 10.1111/bju.12540

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  1. Sarah Payton
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Roehrborn, C. G. et al. The prostatic urethral lift for the treatment of lower urinary tract symptoms associated with prostate enlargement due to benign prostatic hyperplasia: the L.I.F.T. study. J. Urol. 190, 2161–2167 (2013)

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Payton, S. Promising future for the prostatic urethral lift. Nat Rev Urol 10, 677 (2013). https://doi.org/10.1038/nrurol.2013.267

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