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fMRI developments promise understanding of voiding dysfunction

Nature Reviews Urology volume 11, page 303 (2014)Cite this article

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A new paper has provided data on the neurological pathways activated during the voiding stage of micturition, which might facilitate delineation of the aetiological underpinnings of voiding dysfunction in patients who cannot initiate urination.

The study confirmed that brain regions implicated in micturition were activated: a focal region of the pons that initiates urination (the pontine micturition centre [PMC]); motor and executive centres, which might coordinate voiding; and areas linked to emotion, possibly related to the sensations of urination. Importantly, network analysis, based on BOLD-signal sequences, identified short-range and long-range connectivity between the PMC and other neuronal clusters during initiation of voiding.

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References

  1. Shy, M. et al. Functional magnetic resonance imaging during urodynamic testing identifies brain structures initiating micturition. J. Urol. 10.1016/j.juro.2014.04.090

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  1. David Killock
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Killock, D. fMRI developments promise understanding of voiding dysfunction. Nat Rev Urol 11, 303 (2014). https://doi.org/10.1038/nrurol.2014.113

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  • DOI: https://doi.org/10.1038/nrurol.2014.113

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