Premature ejaculation (PE) is a common ailment in men but its pathophysiology remains unclear. Updated guidelines from the International Society of Sexual Medicine attempt to aid the diagnosis and treatment of PE, and here we give our opinion on the best course of action for affected patients.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Porst, H. et al. The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Eur. Urol. 51, 816–824 (2007).
Burri, A., Giuliano, F., McMahon, C. & Porst, H. Female partner's perception of premature ejaculation and its Impact on relationship breakups, relationship quality, and sexual satisfaction. J. Sex. Med. http://dx.doi.org/10.1111/jsm.12551.
Althof, S. E. et al. An update of the International Society of Sexual Medicine's Guidelines for the diagnosis and treatment of premature ejaculation (PE). J. Sex. Med. 11, 1392–1422 (2014).
McMahon, C. G. et al. Efficacy and safety of dapoxetine for the treatment of premature ejaculation: Integrated analysis of results from five phase 3 trials. J. Sex. Med. 8, 524–539 (2011).
Jannini, E. A., McMahon, C., Chen, J., Aversa, A. & Perelman, M. The controversial role of phosphodiesterase type 5 inhibitors in the treatment of premature ejaculation. J. Sex. Med. 8, 2135–2143 (2011).
Jannini, E. A., Isidori, A. M., Aversa, A., Lenzi, A. & Althof, S. E. Which is first? The controversial issue of precedence in the treatment of male sexual dysfunctions. J. Sex. Med. 10, 2359–69 (2013).
Gareri, P., Castagna, A., Francomano, D., Cerminara, G. & De Fazio, P. Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives. Int. J. Endocrinol. http://dx.doi.org/10.1155/2014/878670.
Francomano, D., Donini, L. M., Lenzi, A. & Aversa, A. Peripheral arterial tonometry to measure the effects of vardenafil on sympathetic tone in men with lifelong premature ejaculation. Int. J. Endocrinol. http://dx.doi.org/10.1155/2013/394934.
Carson, C. & Wylie, M. Improved ejaculatory latency, control and sexual satisfaction when PSD502 is applied topically in men with premature ejaculation: results of a phase III, double-blind, placebo-controlled study. J. Sex. Med. 7, 3179–3189 (2010).
Kaynar, M., Kilic, O. & Yurdakul, T. On-demand tramadol hydrochloride use in premature ejaculation treatment. Urology 79, 145–149 (2012).
Acknowledgements
The authors wish to thank Dr Davide Francomano for drawing the algorithm and for his critical review of the manuscript.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
PowerPoint slides
Rights and permissions
About this article
Cite this article
Aversa, A., Lenzi, A. A practical approach to men with premature ejaculation. Nat Rev Urol 11, 496–498 (2014). https://doi.org/10.1038/nrurol.2014.203
Published:
Issue date:
DOI: https://doi.org/10.1038/nrurol.2014.203
This article is cited by
-
Hormonal correlations of premature ejaculation
Endocrine (2015)
