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Prostate cancer

MRI reduces low-risk prostate cancer diagnosis and biopsy

Nature Reviews Urology volume 11, page 245 (2014)Cite this article

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An MRI-based biopsy protocol—involving noninvasive screening by 3T MRI, followed by selective magnetic resonance-guided biopsy (MRGB) of any identified equivocal or suspicious prostatic lesions—has been shown to reduce the diagnosis of low-risk prostate cancer compared with the current diagnostic standard, transrectal ultrasonography-guided biopsy (TRUSGB).

In recent years, use of multiparametric (mp) MRI has improved image-based diagnosis of solid organ tumours, but until now it has not been definitively compared with TRUSGB in the same men for detection of prostate cancer. In a study led by Leslie Thompson of The Wesley Hospital in Brisbane, Australia, 223 consecutive biopsy-naive men with elevated PSA and/or abnormal digital rectal examination results were examined using both mpMRI and TRUSGB.

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References

  1. Pokorny, M. R. et al. Prospective study of diagnostic accuracy comparing prostate cancer detection by transrectal ultrasound-guided biopsy versus magnetic resonance (MR) imaging with subsequent MR-guided biopsy in men without previous prostate biopsies. Eur. Urol. 10.1016/j.eururo.2014.03.002

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  1. Robert Phillips
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Phillips, R. MRI reduces low-risk prostate cancer diagnosis and biopsy. Nat Rev Urol 11, 245 (2014). https://doi.org/10.1038/nrurol.2014.77

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