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References
Duarte, A., Pu, K. -Y., Liu, B. & Bazan, G. Recent Advances in conjugated polyelectrolytes for emerging optoelectronic applications. Chem. Mater. 23, 501–515 (2011).
Elabd, Y. & Hickner, M. Block copolymers for fuel cells. Macromolecules 44, 1–11 (2011).
Sun, H., Meng, F., Dias, A., Hendriks, M., Feijen, J. & Zhong, Z. α-Amino acid containing degradable polymers as functional biomaterials: rational design, synthetic pathway, and biomedical applications. Biomacromolecules 12, 1937–1955 (2011).
Jeong, B., Bae, Y., Lee, D. & Kim, S. Biodegradable block copolymers as injectable drug-delivery systems. Nature 388, 860–862 (1997).
Kimura, Y. Molecular, structural, and material design of bio-based polymers. Polym. J. 41, 797–807 (2009).
Nederberg, F., Connor., E., Möller, M., Glauser, T. & Hedrick, J. New paradigms for organic catalysts: the first organocatalytic living polymerization. Angew. Chem. Int. Ed. 40, 2712–2715 (2001).
Li, Y., Li, Q., Li, F., Zhang, H., Jia, L., Yu, J., Fang, Q. & Cao, A. Amphiphilic poly(L-lactide)-b-dendritic poly(L-lysine)s synthesized with a metal-free catalyst and new dendron initiators: chemical preparation and characterization. Biomacromolecules 7, 224–231 (2006).
Satoh, T., Tamaki, M., Kitajyo, Y., Maeda, T., Ishihara, H., Imai, T., Kaga, H. & Kakuchi, T. Synthesis of unimolecular reversed micelle consisting of a poly(L-lactide) shell and hyperbranched D-mannan core. J. Polym. Sci. A Pol. Chem. 44, 406–413 (2006).
Yan, C., Zhang, J., Lv, Y., Yu, J., Wu, J., Zhang, J. & He, J. Thermoplastic cellulose-graft-poly(L-lactide) copolymers homogeneously synthesized in an ionic liquid with 4-dimethylaminopyridine catalyst. Biomacromolecules 10, 2013–2018 (2009).
Rashkov, I., Manolova, N., Li, S., Espartero, J. & Vert, M. Synthesis, characterization, and hydrolytic degradation of PLA/PEO/PLA triblock Copolymers with short poly(L-lactic acid) chains. Macromolecules 29, 50–56 (1996).
Li, S., Rashkov, I., Espartero, J., Manolova, N. & Vert, M. Synthesis, Characterization, and hydrolytic degradation of PLA/PEO/PLA triblock copolymers with long poly(L-lactic acid) blocks. Macromolecules 29, 57–62 (1996).
Liu, L., Li, C., Liu, X. & He, B. Micellar formation in aqueous milieu from biodegradable triblock copolymer polylactide/poly(ethylene glycol)/polylactide. Polym. J. 31, 845–850 (1999).
Nagahama, K., Ohya, Y. & Ouchi, T. Synthesis of star-shaped 8 arms poly(ethylene glycol)-poly(L-lactide) block copolymer and physicochemical properties of its solution cast film as soft biomaterial. Polym. J 38, 852–860 (2006).
Yang, L., El Ghzaoui, A. & Li, S. In vitro degradation behavior of poly(lactide)–poly(ethylene glycol) block copolymer micelles in aqueous solution. Int. J. Pharm. 400, 96–103 (2010).
Porjazoska, A., Dimitrov, P., Dimitrov, I., Cvetkovska, M. & Tsvetanov, C. Synthesis and aqueous solution properties of functionalized and thermoresponsive poly(D,L-lactide/polyether) block copolymers. Macromol. Symp. 210, 427–436 (2004).
Guan, H., Xie, Z., Zhang, P., Deng, C., Chen, X. & Jing, X. Synthesis and characterization of biodegradable amphiphilic triblock copolymers containing L-glutamic acid units. Biomacromolecules 6, 1954–1960 (2005).
Deng, C., Chen, X., Yu, H., Sun, J., Lu, T. & Jing, X. A biodegradable triblock copolymer poly(ethylene glycol)-bpoly(L-lactide)-b-poly(L-lysine): Synthesis, self-assembly, and RGD peptide modification. Polymer 48, 139–149 (2007).
Hrkach, J., Ou, J., Lotan, N. & Langer, R. Synthesis of poly(L-lactic acid-co-L-lysine) graft copolymers. Macromolecules 28, 4736–4739 (1995).
Dimitrov, I. & Berlinova, I. Synthesis of poly(ethylene oxide)s bearing functional groups along the chain. Macromol. Rapid Commun. 24, 551–555 (2003).
Dimitrov, I., Berlinova, I. & Vladimirov, N. Synthesis of poly(oxyethylene)-poly(Z-L-lysine) hybrid graft copolymers. Macromolecules 39, 2423–2426 (2006).
Rostovtsev, V., Green, L., Fokin, V. & Sharpless, K. A stepwise Huisgen cycloaddition process: copper(I)-catalyzed regioselective “ligation” of azides and terminal alkynes. Angew. Chem. Int. Ed. 41, 2596–2599 (2002).
Gautier, A., Pitrat, D. & Hasserodt, J. An unusual functional group interaction and its potential to reproduce steric and electrostatic features of the transition states of peptidolysis. Bioorg. Med. Chem. 14, 3835–3847 (2006).
Li, Y., Yang, J. & Benicewicz, B. Well-controlled polymerization of 2-azidoethyl methacrylate at near room temperature and click functionalization. J. Polym. Sci. A Pol. Chem. 45, 4300–4308 (2007).
Binder, W. & Sachsenhofer, R. “Click” chemistry in polymer and material science: an update. Macromol. Rapid Commun. 29, 952–981 (2008).
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Support of this research by the Bulgarian National Science Fund, through Project DCVP-02/2/2009, National Centre for New Materials UNION is gratefully acknowledged.
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Dimitrov, I., Berlinova, I. & Michailova, V. Synthesis of multifunctional poly(D,L-lactide)-poly(oxyethylene)-poly(D,L-lactide) triblock copolymers. Polym J 45, 457–461 (2013). https://doi.org/10.1038/pj.2012.155
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DOI: https://doi.org/10.1038/pj.2012.155