INSULIN, PROINSULIN AND INSULINE-LIKE GROWTH FACTOR I (IGF I) IN LARGE (LGA) AND APPROPRIATE (AGA) TERM NEWBORN INFANTS OF NON-DIABETIC MOTHERS.† 1245

The goal of this study was to verify if endocrine factors play some role in the determination of the birth weight in healthy term newborn infants. Patients included 21 LGA (mean BW= 3998g, 58% male, 50% vaginal delivery) and 39 AGA (mean BW= 3189g, 51% male, 71% vaginal delivery) infants of non-diabetic mothers with an uneventful prenatal care and without perinatal asphyxia or congenital malformations. Cord blood and 48-72 h. of life peripheral blood samples were drawn in order to perform the following tests: plasma glucose by glucose-oxydase method, serum insulin and proinsulin by immunofluorometry, and IGF I by radioimmunoassay.

Results are expressed in median (variation). Non-parametric tests were performed with rejection level of 0.05. Table

Table 1

Log in or create a free account to read this content

Gain free access to this article, as well as selected content from this journal and more on nature.com

Access through your institution

or

Sign in or create an account

Continue with Google

Continue with ORCiD