Abstract 1082

Background. IV fluids are usually administered to LBW infants to prevent hypoglycemia while full enteral feedings are reached. Aim. To evaluate feasibility of CGD for fluid administration in LBW infants. Design and settings. Randomized controlled two center trial. Primary outcome measure was need for IV access. Methods. 1500-2000g infants whose attending physician ordered IV fluids were randomized during the first two h of life to CGD or IV fluids. Infants with 5′Apgar < 6, blood sugar ≤ 20mg/dl at two h of life, hematocrit > 65%, RDS (FiO2 > 30), hemodynamic inestability or major congenital malformation were excluded. Fluid (D10w) and enteral volume management were the same for both groups. Serial blood sugar and serum electrolytes measurements were performed during the first 72 h after randomization. Blood sugar < 40 mg/dl, bloody or bilious residuals, residuals volume greater than 50% of the volume administered over the 3 previous or 2 or more vomiting episodes in 24 h were considered failure criteria for CGD, and patients crossed over IV fluid group. Results. In CGD group one infant died, transverse sinus thrombosis, and one received IV fluids because blood sugar < 40 mg/dl. (Table)

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