Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Bode L 2006 Recent advances on structure, metabolism, and function of human milk oligosaccharides. J Nutr 136: 2127–2130
Moro G, Minoli I, Mosca M, Fanaro S, Jelinek J, Stahl B, Boehm G 2002 Dosage-related bifidogenic effects of galacto—and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr 34: 291–295
Costalos C, Kapiki A, Apostolou M, Papathoma E 2008 The effect of a prebiotic supplemented formula on growth and stool microbiology of term infants. Early Hum Dev 84: 45–49
Vos AP, Haarman M, Buco A, Govers M, Knol J, Garssen J, Stahl B, Boehm G, M'Rabet L 2006 A specific prebiotic oligosaccharide mixture stimulates delayed-type hypersensitivity in a murine influenza vaccination model. Int Immunopharmacol 6: 1277–1286
Arslanoglu S, Moro GE, Boehm G 2007 Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr 137: 2420–2424
Moro G, Arslanoglu S, Stahl B, Jelinek J, Wahn U, Boehm G 2006 A mixture of prebiotic oligosaccharides reduces the incidence of atopic dermatitis during the first six months of age. [see comment]. Arch Dis Child 91: 814–819
Barrat E, Michel C, Poupeau G, David-Sochard A, Rival M, Pagniez A, Champ M, Darmaun D 2008 Supplementation with galactooligosaccharides and inulin increases bacterial translocation in artificially reared newborn rats. Pediatr Res 64: 34–39
Ten Bruggencate SJ, Bovee-Oudenhoven IM, Lettink-Wissink ML, Van der Meer R 2003 Dietary fructo-oligosaccharides dose-dependently increase translocation of Salmonella in rats. J Nutr 133: 2313–2318
Ten Bruggencate SJ, Bovee-Oudenhoven IM, Lettink-Wissink ML, Van der Meer R 2005 Dietary fructooligosaccharides increase intestinal permeability in rats. J Nutr 135: 837–842
Ten Bruggencate SJ, Bovee-Oudenhoven IM, Lettink-Wissink ML, Katan MB, van der Meer R 2006 Dietary fructooligosaccharides affect intestinal barrier function in healthy men [see comment]. J Nutr 136: 70–74
Catassi C, Bonucci A, Coppa GV, Carlucci A, Giorgi PL 1995 Intestinal permeability changes during the first month: effect of natural versus artificial feeding. J Pediatr Gastroenterol Nutr 21: 383–386
Colome G, Sierra C, Blasco J, Garcia MV, Valverde E, Sanchez E 2007 Intestinal permeability in different feedings in infancy. Acta Paediatr 96: 69–72
Alverdy JC, Chang EB 2008 The re-emerging role of the intestinal microflora in critical illness and inflammation: why the gut hypothesis of sepsis syndrome will not go away. J Leukoc Biol 83: 461–466
Raymond DP, Pelletier SJ, Crabtree TD, Gleason TG, Pruett TL, Sawyer RG 2001 Impact of bloodstream infection on outcomes among infected surgical inpatients. Ann Surg 233: 549–555
Alverdy JC, Laughlin RS, Wu L 2003 Influence of the critically ill state on host-pathogen interactions within the intestine: gut-derived sepsis redefined. Crit Care Med 31: 598–607
Swennen K, Courtin CM, Delcour JA 2006 Non-digestible oligosaccharides with prebiotic properties. Crit Rev Food Sci Nutr 46: 459–471
Newburg DS, Ruiz-Palacios GM, Morrow AL 2005 Human milk glycans protect infants against enteric pathogens. Annu Rev Nutr 25: 37–58
Angeloni S, Ridet JL, Kusy N, Gao H, Crevoisier F, Guinchard S, Kochhar S, Sigrist H, Sprenger N 2005 Glycoprofiling with micro-arrays of glycoconjugates and lectins. Glycobiology 15: 31–41
Kuntz S, Rudloff S, Kunz C 2008 Oligosaccharides from human milk influence growth-related characteristics of intestinally transformed and non-transformed intestinal cells. Br J Nutr 99: 462–471
Obermeier S, Rudloff S, Pohlentz G, Lentze MJ, Kunz C 1999 Secretion of 13C-labelled oligosaccharides into human milk and infant's urine after an oral [13C]galactose load. Isotopes Environ Health Stud 35: 119–125
Rudloff S, Stefan C, Pohlentz G, Kunz C 2002 Detection of ligands for selectins in the oligosaccharide fraction of human milk. Eur J Nutr 41: 85–92
Bode L, Kunz C, Muhly-Reinholz M, Mayer K, Seeger W, Rudloff S 2004 Inhibition of monocyte, lymphocyte, and neutrophil adhesion to endothelial cells by human milk oligosaccharides. Thromb Haemost 92: 1402–1410
Bode L, Rudloff S, Kunz C, Strobel S, Klein N 2004 Human milk oligosaccharides reduce platelet-neutrophil complex formation leading to a decrease in neutrophil beta 2 integrin expression. J Leukoc Biol 76: 820–826
Seifert S, Watzl B 2007 Inulin and oligofructose: review of experimental data on immune modulation. J Nutr 137: 2563S–2567S
LoCascio RG, Ninonuevo MR, Freeman SL, Sela DA, Grimm R, Lebrilla CB, Mills DA, German JB 2007 Glycoprofiling of bifidobacterial consumption of human milk oligosaccharides demonstrates strain specific, preferential consumption of small chain glycans secreted in early human lactation. J Agric Food Chem 55: 8914–8919
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Ninonuevo, M., Bode, L. Infant Formula Oligosaccharides Opening the Gates (for Speculation): Commentary on the article by Barrat et al. on page 34. Pediatr Res 64, 8–10 (2008). https://doi.org/10.1203/PDR.0b013e3181752c2f
Received:
Accepted:
Issue date:
DOI: https://doi.org/10.1203/PDR.0b013e3181752c2f